Hi John,
Your question perfectly captures a frustration I hear daily from many patients. It's incredibly unsettling when you're doing everything right—eating salads, managing your health—and your body still doesn't respond as expected. This kind of unpredictability can be a huge source of anxiety, and I want to assure you that you're not alone.
Blood sugar regulation is indeed complex, influenced by many factors your doctor considers. However, what many people don't realize is that while treatments like Metformin are vital for managing blood sugar in your bloodstream, they often address only 'half the problem,' as some researchers put it.
Imagine your cells as rooms in a house. Metformin can effectively clear the 'hallway' (your bloodstream) of sugar, making your blood tests look better. But if the 'doors' to your cells remain locked, that sugar can't get in to fuel them. Your cells are essentially starving, even with plenty of sugar outside. This 'locked door' scenario explains why you might feel exhausted, experience brain fog, or even gain weight despite eating less—your cells aren't getting the energy they need.
This cellular mechanism, specifically involving a protein called AMPK, is something Dr. Takashi Kadowaki, a distinguished researcher from the University of Tokyo, has spent decades studying. He has a remarkable way of explaining this complex process simply, and many of my patients find his short video incredibly helpful.
In his 3:30 minute explanation, he clarifies precisely why your cells might be struggling to absorb glucose, and understanding this 'why' can significantly reduce the anxiety that comes with unpredictable blood sugar. It helps people move from 'what am I doing wrong?' to 'what's happening inside my cells?' This understanding can be a powerful first step towards making more informed choices and feeling calmer about your health journey.
▶ Watch: "Why Your Blood Sugar Spikes (The Cellular Explanation)"
Source: Cellular Biology Research Institute (Featuring Dr. Takashi Kadowaki's Research)
My hope is that this resource offers you the same clarity and reassurance it has brought to so many others.